Error with pre-create check: “This computer doesn't have VT-X/AMD-v enabled. Enabling it in the BIOS is mandatory” even though it's enabled

The same issue on Windows 10 Home with Docker Toolbox 18.09.3 (laptop powered by Ryzen 2500U): running normal Linux image via Virtualbox works like a charm, and msinfo32 tool reports "virtualization enabled: true"

What helped was adding --virtualbox-no-vtx-check to the docker-machine create command, to be more specific I used this cmd:

docker-machine create -d virtualbox --virtualbox-memory=4096 \
    --virtualbox-cpu-count=4 --virtualbox-disk-size=40960 \
    --virtualbox-no-vtx-check default

And everything worked just great! 

Hope this helps on your case as well :-)